What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Healthy (n=800). Intervention: U.S. nationality vs. Japanese nationality. Primary outcome: Indices of arterial stiffness, including carotid-femoral (cfPWV) and brachial-ankle pulse wave velocity (baPWV).

What does this research mean for the field?

Age-associated increases in central arterial stiffness are significantly greater in healthy American women than in Japanese women, whereas age-related arterial stiffening rates do not differ between American and Japanese men. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 1, 2015Journal of the American Geriatrics Society

Attenuated Age‐Related Increases in Arterial Stiffness in Japanese and American Women

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Key result

Age-related cfPWV increases more in healthy U.S. women than Japanese women, unlike men.

n=800

Population

800 healthy, nonsmoking adults without cardiovascular and other chronic diseases (n=400 Japanese, n=400 U.S.)

Design

Cross-sectional

Authors

HTHirofumi Tanaka MMMotohiko Miyachi HMHaruka Murakami

Discussion

Member takes

Overview

Differences in arterial stiffness may inform sex-specific risk assessment across populations; leaves open mechanisms driving ethnic disparities in women's vascular aging.

Study Design

Type

Cross-Sectional (n=800)

Multicenter

Yes

Structured PICO

Population

800 healthy, nonsmoking adults without cardiovascular or chronic diseases from the U.S. and Japan.

Outcome

Age-related increases in arterial stiffness, measured by carotid-femoral (cfPWV) and brachial-ankle pulse wave velocity (baPWV)surrogate

Japanese women exhibit smaller age-related increases in central arterial stiffness compared to U.S. women, which may provide insight into inter-country differences in life expectancy.

Cite This Study

Tanaka et al. (2015) conducted a cross-sectional in Healthy (n=800). U.S. nationality vs. Japanese nationality was evaluated on Indices of arterial stiffness, including carotid-femoral (cfPWV) and brachial-ankle pulse wave velocity (baPWV). Age-associated increases in central arterial stiffness (cfPWV) were significantly greater in healthy U.S. women compared with Japanese women, with no differences observed between men.

synapsesocial.com/papers/6aa5624c24014aaf7fdd476f https://doi.org/10.1111/jgs.13433

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June 1, 2015Journal of the American Geriatrics Society

Attenuated Age‐Related Increases in Arterial Stiffness in Japanese and American Women

View Full Paper

Ask AI

Bookmark

Key result

Age-related cfPWV increases more in healthy U.S. women than Japanese women, unlike men.

n=800

Population

800 healthy, nonsmoking adults without cardiovascular and other chronic diseases (n=400 Japanese, n=400 U.S.)

Design

Cross-sectional

Authors

HTHirofumi Tanaka MMMotohiko Miyachi HMHaruka Murakami

Discussion

Member takes

Overview

Differences in arterial stiffness may inform sex-specific risk assessment across populations; leaves open mechanisms driving ethnic disparities in women's vascular aging.

Study Design

Type

Cross-Sectional (n=800)

Multicenter

Yes

Structured PICO

Population

800 healthy, nonsmoking adults without cardiovascular or chronic diseases from the U.S. and Japan.

Outcome

Age-related increases in arterial stiffness, measured by carotid-femoral (cfPWV) and brachial-ankle pulse wave velocity (baPWV)surrogate

Japanese women exhibit smaller age-related increases in central arterial stiffness compared to U.S. women, which may provide insight into inter-country differences in life expectancy.

Cite This Study

synapsesocial.com/papers/6aa5624c24014aaf7fdd476f https://doi.org/10.1111/jgs.13433

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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