Octakis(3,6-anhydro)-γ-cyclodextrin 3 has been prepared by the reaction of octakis (6-O-tosyl)-γ- Cyclodextrin with KOH; 3 shows a specific binding ability to alkali metal ions with larger ionic diameters, owing to its hydrophilic cavity which is similar to the layered crown ethers.
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Yamamura et al. (1993) studied this question.
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