Answers are grounded in this paper and cite their sources.
Alkyl-, aryl-and hetaryl ketones after a one-pot oximation and treatment with acetylene are converted to 2-mono-and 2,3-disubstituted NHand N-vinylpyrroles with alkyl-, aryl-and hetaryl substituents in good yields. The oximation is effected using a NH 2 OHHCl-NaHCO 3 system at room temperature. The reaction with acetylene is carried out in the presence of the KOH/DMSO superbase at 100 o C under atmospheric pressure.
No takes yet. Share an insight, caveat, or question.
Schmidt et al. (2005) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: