Key result
Younger patients with uncomplicated apparently treatment-resistant hypertension had a significantly higher rate of total non-adherence to antihypertensive drugs compared to older or complicated patients (24.1% vs 7.1%, P=0.026).
Why the study?
The study aimed to evaluate drug adherence and its association with psychological factors and hypertension severity across two subtypes of apparently treatment-resistant hypertension.
Population
Patients with apparently treatment-resistant hypertension, including 54 younger uncomplicated and 43 older or complicated patients
Comparison
Younger patients with uncomplicated hypertension (YURHTN) vs older/complicated patients (OCRHTN)
Authors
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May support targeted adherence screening in younger uncomplicated aTRH; hypothesis-generating for age-specific strategies in resistant hypertension.
Cross-Sectional (n=97)
Yes
Absolute Event Rate: 24.1% vs 7.1%
p-value: p=0.026
Younger patients with uncomplicated treatment-resistant hypertension have significantly lower drug adherence and distinct psychological predictors of disease severity compared to older or complicated patients.
Georges et al. (2022) conducted a cross-sectional in Apparently treatment-resistant hypertension (ATRH) (n=97). Younger age and absence of cardiovascular complications (YURHTN) vs. Age ≥60 years and/or history of cardiovascular complications (OCRHTN) was evaluated on Total non-adherence to antihypertensive drugs (p=0.026). Younger patients with uncomplicated apparently treatment-resistant hypertension had a significantly higher rate of total non-adherence to antihypertensive drugs compared to older or complicated patients (24.1% vs 7.1%, P=0.026).
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