Key result
Psychological factors, including somatisation and low acceptance, independently predicted poor drug adherence (explaining 41% of variability) and hypertension severity (63%) in ATRH patients.
Why the study?
Prior pilot data in 35 patients linked psychological profile, drug adherence, and hypertension severity; this study aimed to confirm and expand those findings in a larger, more representative sample of patients with apparently treatment-resistant hypertension.
Are psychological factors associated with drug adherence and severity of hypertension in patients with apparently treatment-resistant hypertension compared to controlled hypertension?
Cross-Sectional
Yes
Are psychological factors associated with drug adherence and severity of hypertension in patients with apparently treatment-resistant hypertension compared to controlled hypertension?
p-value: p=0.022
Psychological factors, particularly somatisation and expression of emotions, are strong independent predictors of poor drug adherence and hypertension severity in patients with apparently treatment-resistant hypertension.
Psychological assessment may identify adherence barriers in ATRH; hypothesis-generating for interventions, should not yet change practice.
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Georges et al. (2022) conducted a cross-sectional in Apparently treatment-resistant hypertension (ATRH). Apparently treatment-resistant hypertension (ATRH) vs. Controlled hypertension was evaluated on Predictors of poor drug adherence and severity of hypertension (p=0.022). Psychological factors, including somatisation and low acceptance, independently predicted poor drug adherence (explaining 41% of variability) and hypertension severity (63%) in ATRH patients.
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