Why the study?
What are the clinical circumstances and triggers leading to Torsades de Pointes in patients previously treated with anthracyclines?
Population
11 patients from 9 literature reports who developed Torsades de Pointes weeks to years following previous…
Design
Systematic_review
Follow-up
weeks to years following treatment
Authors
Loading...
Clinicians should avoid QT-prolonging agents and correct hypokalemia in anthracycline-treated patients; extends TdP trigger profile to this population.
What are the clinical circumstances and triggers leading to Torsades de Pointes in patients previously treated with anthracyclines?
Previous treatment with anthracyclines is an under-recognized risk factor for Torsades de Pointes, particularly in women exposed to QT-prolonging agents like azoles or hypokalemia.
Arbel et al. (2007) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: