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February 1, 1991Pacing and Clinical Electrophysiology

Resolution of High Initial Epicardial Patch Defibrillation Thresholds Following Chronic Implantation

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Key result

Chronic implantation of epicardial patch electrodes for 10-15 days achieved adequate defibrillation thresholds (mean 18 joules) in 100% of patients who initially failed testing.

Why the study?

Does chronic implantation of epicardial patch electrodes improve high initial defibrillation thresholds in patients undergoing ICD placement?

Population

6 patients with coronary artery disease or dilated cardiomyopathy, mean ejection fraction 20%, who had…

Comparison

Chronic implantation of epicardial patch… vs Initial implant testing (baseline).

Design

Case_series

Follow-up

10-15 days (mean 11 days)

Authors

BGBlair P. GrubbElectrophysiologyMMMary C. ManciniLeicester City CouncilPTPeter N. Temesy‐ArmosUniversity of Toledo Medical Center

Discussion

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Implication

May allow ICD success after initial DFT failure; hypothesis-generating from case report and needs prospective validation.

Study Design

Type

Observational (n=6)

Structured PICO

Does chronic implantation of epicardial patch electrodes improve high initial defibrillation thresholds in patients undergoing ICD placement?

P
Population
6 patients (mean age 61 years, 17% female) with high initial epicardial patch defibrillation thresholds and profound hypotension at implant, retested after 10-15 days.
I
Intervention
Chronic implantation of epicardial patch electrodes in an arbitrary anterior-posterior position with leads tunneled to an abdominal pocket, followed by retesting after 10-15 days.
C
Comparator
Initial implant testing (baseline).
O
Outcome
Defibrillation thresholds at 10-15 days post-implant.surrogate

Main Result

Absolute Event Rate: 100% vs 0%

Chronic implantation of epicardial patch electrodes for 10-15 days allows for adequate defibrillation thresholds in patients with initially unacceptably high thresholds and hemodynamic instability during testing.

Cite This Study

Grubb et al. (1991) conducted an observational in High initial epicardial patch defibrillation thresholds (n=6). Chronic implantation of epicardial patch electrodes vs. Initial implant (baseline) was evaluated on Adequate defibrillation thresholds. Chronic implantation of epicardial patch electrodes for 10-15 days achieved adequate defibrillation thresholds (mean 18 joules) in 100% of patients who initially failed testing.

synapsesocial.com/papers/6a9d96cb612f7f644148b62fhttps://doi.org/10.1111/j.1540-8159.1991.tb05082.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Measurement of cardioversion/defibrillation thresholds in man by a truncated exponential waveform and an apical patch-superior vena caval spring electrode configuration.1984 · 109 citations
  2. 2Internal cardiac defibrillation in man: pronounced improvement with sequential pulse delivery to two different lead orientations.1986 · 117 citations
  3. 3Termination of Malignant Ventricular Arrhythmias with an Implanted Automatic Defibrillator in Human Beings1980 · 1,366 citations
  4. 4Feasibility and Effectiveness of Low-Energy Catheter Defibrillation in Man1973 · 150 citations
  5. 5Mortality in Patients with Implanted Automatic Defibrillators1983 · 311 citations