Why the study?
Do admission ECG parameters predict adverse clinical outcomes in patients with COVID-19?
Meta-Analysis (n=1,424)
Do admission ECG parameters predict adverse clinical outcomes in patients with COVID-19?
Absolute Event Rate: 446.76% vs 423.52%
p-value: p=<0.000001
Admission ECG parameters, specifically prolonged QRS, prolonged QTc, and higher heart rate, are associated with a more severe course of COVID-19 and may aid in early risk stratification.
May aid early risk stratification in COVID-19; hypothesis-generating, needs prospective validation before practice change.
The assessment of the prognostic value of the admission electrocardiography (ECG) (specifically of the duration of the PR and QTc intervals, the QRS complex and the heart rate [HR]) in COVID-19 patients on the basis of nine observational studies (n=1,424) indicates that relatively long duration of the QTc interval and QRS complex, as well as higher HR, are linked to a severe course of COVID-19, which may be of use in risk stratification. Since there are important differences in suggested indicators of adverse prognosis between observational studies, further research is necessary to clarify high-risk criteria.
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Wawrzeńczyk et al. (2022) conducted a meta-analysis in COVID-19 (n=1,424). Adverse clinical outcome (major adverse events, ICU transfer, death) vs. Favorable clinical outcome was evaluated on Mean QTc interval on admission (ms) (p=<0.000001).
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