Esophageal Motility in Neuromuscular Disorders

Article1 August 1965Esophageal Motility in Neuromuscular DisordersROBERT A. FISCHER, M.D., GEORGE W. ELLISON, M.D., WALTER R. THAYER, M.D., HOWARD M. SPIRO, M.D., F.A.C.P., GILBERT H. GLASER, M.D.ROBERT A. FISCHER, M.D., GEORGE W. ELLISON, M.D., WALTER R. THAYER, M.D., HOWARD M. SPIRO, M.D., F.A.C.P., GILBERT H. GLASER, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-2-229 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOne of the frequent problems in patients with neuromuscular disorders is swallowing dysfunction, often leading to a severe nutritional disturbance. Swallowing is a complex phenomenon comprised of the transfer of food from the mouth into the oropharynx, its transport through the esophagus, and its entrance into the stomach. Swallowing is usually an act involving voluntary initiation at a cerebral level with transmission along corticobulbar pathways to the medulla. Transfer combines this volitional act with reflex activity mediated via the glossopharyngeal and vagus nerves in such a way that once the swallow begins it continues through the oropharynx and pharyngeal-esophageal sphincter...References1. NAGLERSPIRO RHH: Serial esophageal motility studies in asymptomatic young subjects. Gastroenterology 41: 371, 1961. CrossrefMedlineGoogle Scholar2. TERRACOLSWEET JRH: Diseases of the Esophagus. W. B. Saunders Co., Philadelphia, 1959, p. 29. Google Scholar3. AREYTREMAINE LBMJ: The muscular content of the lower esophagus in man. Anat. Rec. 56: 315, 1933. CrossrefGoogle Scholar4. SIEGELHARVEYHOOKMANMENDELOFFHENDRIX CIJCPAITR: Dysphagia localized to the hypopharynx and upper esophagus: a cineradiographic and manometric study. Presented at the Forty-fourth Annual Session of The American College of Physicians, Denver, April 3, 1963. Google Scholar5. KELLEY ML: Dysphagia and motor failure of the esophagus in myotonia dystrophica. Neurology 14: 955, 1964. CrossrefMedlineGoogle Scholar6. RUBINNAGLERSPIROPILOT JRHMML: Measuring the effect of emotion of esophageal motility. Psychosom. Med. 24: 170, 1962. CrossrefMedlineGoogle Scholar7. SOERGELZBORALSKEAMBERG KHFFJR: Presbyesophagus: esophageal motility in nonagenarians. J. Clin. Invest. 43: 1472, 1964. CrossrefMedlineGoogle Scholar8. CARVETHSCHLEGELCODEELLIS SWJFCFFH: Esophageal motility after vagotomy, phrenicotomy, myotomy and myomectomy in dogs. Surg. Gynec. Obstet. 114: 31, 1962. MedlineGoogle Scholar9. SMITHMULDERCODE AWDC: Esophageal motility in amyotrophic lateral sclerosis. Proc. Mayo Clin. 32: 438, 1957. MedlineGoogle Scholar10. DALYCODEANDERSEN DDCFHA: Disturbances of swallowing and esophageal motility in patients with multiple sclerosis. Neurology 12: 250, 1962. CrossrefMedlineGoogle Scholar11. DONAGHUEWINKELMANNMOERSCH FRH: Esophageal defects in dermatomyositis. Ann. Otol. 69: 1139, 1960. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New Haven, ConnecticutFrom the Sections of Gastroenterology and Neurology, Department of Medicine, Yale University School of Medicine, New Haven, Conn.This study was supported in part by grants AM 04759, AM 5156, and 5-TI-NB-5030-10 from the U. S. Public Health Service, Bethesda, Md.Dr. Fischer is a Fellow in Gastroenterology, and Dr. Ellison is a Fellow in Neurology.Requests for reprints should be addressed to Howard M. Spiro, M.D., Yale University School of Medicine, 333 Cedar St., New Haven, Conn. 06411. 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HOLLIS, DONALD O. CASTELLDiseases of the Gastrointestinal TractAchalasiaMotor Disorders Due to Muscle DisordersMotor Disorders Due to Lesions of the Central Nervous SystemAmplitude of Esophageal Peristalsis as Determined by Rapid InfusionMultiple lower esophageal diverticula: unusual endoscopic appearanceDysphagiaGastric bezoar in a patient with myotonic dystrophyDiffuse Esophageal Spasm: A Disorder with More Than One CauseEsophageal MotilityEffect of Infusion on Force of Closure Measurements in the Human EsophagusGonorrhea: Not Yet ControllableRAJ K. GOYAL, M.D., HOWARD M. SPIRO, M.D.Unclassified oesophageal motor disorders simulating achalasia.Deterioration of Esophageal Peristalsis in Patients with Alcoholic NeuropathyElectrical activity of striated and smooth muscle of the esophagus 1 August 1965Volume 63, Issue 2Page: 229-248KeywordsMouthMultiple sclerosisNervesNeurologyNutritional deficienciesOropharynxParalysisReflexesStomachSwallowing Issue Published: 1 August 1965 PDF DownloadLoading ...