Key result
Patients with chronic muscle pain have a diminished ability to vasodilate in painful muscle compared to healthy controls, as assessed by near infra-red spectroscopy.
Why the study?
Can near infra-red spectroscopy accurately assess intramuscular haemodynamics and identify differences in vasodilation between chronic muscle pain patients and healthy controls?
Can near infra-red spectroscopy accurately assess intramuscular haemodynamics and identify differences in vasodilation between chronic muscle pain patients and healthy controls?
Near infra-red spectroscopy is a valid non-invasive tool for assessing intramuscular haemodynamics, revealing impaired vasodilation in patients with chronic muscle pain.
NIRS may detect impaired vasodilation in chronic muscle pain; leaves open its diagnostic or therapeutic role pending prospective validation.
Recently, localized intramuscular haemodynamic disturbance has been recognized as one of the cardinal features of a chronically painful muscle. To test this hypothesis, we have carried out several studies that have assessed intramuscular haemodynamics to understand more about haemodynamic alteration under conditions of an experimentally induced vasoreactive challenges in healthy controls and in patients with chronic muscle pain using near infra?red (NIR) spectroscopy. In addition, we have validated the NIR based haemodynamic signals by comparing against a water signal intensity change taken from a transverse T2?weighted magnetic resonance image (MRI) of the muscles. As a result, we discovered that muscle pain patients have a diminished ability to vasodilate in painful muscle. We also provided powerful evidences that NIR data (total haemoglobin level), transcutaneously taken from the muscles in humans could be an analogue of intramuscular haemodynamics.
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Kuboki et al. (2005) conducted a review in chronic muscle pain. near infra-red (NIR) spectroscopy vs. healthy controls was evaluated on intramuscular haemodynamics (ability to vasodilate). Patients with chronic muscle pain have a diminished ability to vasodilate in painful muscle compared to healthy controls, as assessed by near infra-red spectroscopy.
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