Laboratory evaluation demonstrates rapid capillary electrophoresis detection of iopamidol in serum, indicating broad utility for monitoring renal function markers.
A rapid method for the analysis of the contrast agent iopamidol (isovue)in serum by CE is described. The method involves deproteinzation with acetonitrile to remove serum proteins followed by direct capillary zone electrophoresis. It is rapid(about 10 min) and sensitive. Other contrast agents and compounds used for renal function tests such as iohexol, iothalamic acid and p-aminohippuric acid can be detected by the same method. The use of acetonitrile in this method to remove serum proteins results in sample stacking allowing the detection of levels less than 1 mg/L.
No takes yet. Share an insight, caveat, or question.
Shihabi et al. (1995) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: