Key result
Direct HPLC injection of diluted serum enables iohexol measurement in ~5 minutes.
Design
Other
Authors
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May accelerate iohexol GFR testing turnaround; leaves open prospective clinical validation before routine use.
Direct injection of diluted serum onto an HPLC column allows for rapid determination of iohexol in under 5 minutes.
Shihabi et al. (1993) studied this question. Direct injection of 200-fold diluted serum onto an HPLC column enabled the measurement of iohexol in less than 5 minutes.
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