Key result
Percutaneous balloon aortic valvotomy significantly decreased the mean peak systolic aortic valve gradient from 122 to 43 mmHg (P<0.01) in patients with severe congenital aortic stenosis.
Why the study?
Does percutaneous balloon aortic valvotomy reduce peak systolic aortic valve gradient in adolescents and young adults with severe congenital aortic stenosis?
Population
6 consecutive adolescents and young adults with severe congenital aortic valvular stenosis, mean age 18 +/…
Design
Case_series
Follow-up
1-6 months
Authors
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Acute gradient reduction feasible in young patients with congenital AS; hypothesis-generating and should not yet change practice.
Observational (n=6)
Does percutaneous balloon aortic valvotomy reduce peak systolic aortic valve gradient in adolescents and young adults with severe congenital aortic stenosis?
Absolute Event Rate: 43% vs 122%
p-value: p=<0.01
Percutaneous balloon aortic valvotomy is feasible and significantly reduces peak systolic aortic valve gradient in adolescents and young adults with severe congenital aortic stenosis.
Ribeiro et al. (1988) conducted an observational in Severe congenital aortic valvular stenosis (n=6). Percutaneous balloon aortic valvotomy vs. Baseline (pre-valvotomy) was evaluated on Mean peak systolic aortic valve gradient (PSG) (p=<0.01). Percutaneous balloon aortic valvotomy significantly decreased the mean peak systolic aortic valve gradient from 122 to 43 mmHg (P<0.01) in patients with severe congenital aortic stenosis.
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