Key result
Family association of cardiac disease, acute rheumatic fever, and chorea is frequently observed, while syphilis is rarely an etiologic factor in cardiac disease in persons under 35 years of age.
Highlights the historical recognition of familial clustering in cardiac disease, acute rheumatic fever, and chorea.
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Supports family history assessment in young cardiac patients; leaves open modern validation of these associations.
William St. Lawrence (1922) conducted a review in Cardiac disease, acute rheumatic fever, and chorea. Family association of cardiac disease, acute rheumatic fever, and chorea is frequently observed, while syphilis is rarely an etiologic factor in cardiac disease in persons under 35 years of age.
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