Key result
Gated myocardial perfusion imaging by 99mTc-sestamibi SPECT immediately after primary PCI significantly correlated with final infarct size, left ventricular volumes, and function at 3 months.
Why the study?
Does gated 99mTc-sestamibi SPECT immediately after primary PCI predict final infarct size and left ventricular function at 3 months in patients with acute myocardial infarction?
Observational (n=19)
Does gated 99mTc-sestamibi SPECT immediately after primary PCI predict final infarct size and left ventricular function at 3 months in patients with acute myocardial infarction?
Gated 99mTc-sestamibi SPECT performed immediately after primary PCI can predict final infarct size and left ventricular function at 3 months, offering a potential tool for early risk stratification.
Answers are grounded in this paper and cite their sources.
May support early post-PCI risk stratification; leaves open whether gated SPECT improves outcomes over standard measures.
Following an acute myocardial infarction, the size of the infarct and the resulting left ventricular volume and function are important predictors of mortality. Identifying patients with impaired tissue level perfusion after percutaneous coronary intervention (PCI) for myocardial infarction therefore could have prognostic implications. To obtain combined measures of left ventricular perfusion, volumes and function we applied a gated myocardial perfusion imaging by (99m)Tc-sestamibi single photon emission computerized tomography to 19 patients immediately after revascularization by PCI and repeated this after 3 months. The results of the acute myocardial perfusion imaging significantly correlated to final infarct size, left ventricular volumes and function 3 months later. It is concluded that the method holds the potential for risk stratifying patients immediately after revascularization for acute myocardial infarction.
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Kaltoft et al. (2003) conducted an observational in Acute myocardial infarction (n=19). Gated myocardial perfusion imaging by 99mTc-sestamibi SPECT was evaluated on Correlation to final infarct size, left ventricular volumes and function 3 months later. Gated myocardial perfusion imaging by 99mTc-sestamibi SPECT immediately after primary PCI significantly correlated with final infarct size, left ventricular volumes, and function at 3 months.
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