May 1, 1991Circulation
Noninvasive identification of myocardium at risk in patients with acute myocardial infarction and nondiagnostic electrocardiograms with technetium-99m-Sestamibi.
Why the study?
Does technetium-99m-Sestamibi imaging identify myocardium at risk in patients with acute myocardial infarction and nondiagnostic electrocardiograms?
Population
14 patients who had chest pain without ST elevation, who subsequently developed enzymatic evidence of…
Design
Case_series
Follow-up
within 24 hours
Authors
Discussion
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Member takes
Implication
Suggests sestamibi imaging identifies at-risk myocardium despite nondiagnostic ECGs; hypothesis-generating, needs prospective validation.
Structured PICO
Does technetium-99m-Sestamibi imaging identify myocardium at risk in patients with acute myocardial infarction and nondiagnostic electrocardiograms?
P
Population
14 patients who had chest pain without ST elevation, who subsequently developed enzymatic evidence of myocardial infarction within 24 hours.
I
Intervention
Technetium-99m-Sestamibi injection during chest pain followed by tomographic imaging 1-6 hours after injection.
O
Outcome
Presence of significant perfusion defects indicative of acute myocardial infarction.surrogate
Technetium-99m-Sestamibi imaging can identify significant myocardium at risk in patients with acute MI and nondiagnostic ECGs, potentially guiding early reperfusion therapy.
Cite This Study
Christian et al. (1991) studied this question.