Key result
Resting 99mTc-sestamibi SPECT redistribution post-thrombolytic therapy predicted the recovery of segmental wall motion abnormality in patients with acute myocardial infarction (p<0.001).
Why the study?
Can rest 99mTc-sestamibi SPECT predict the recovery of myocardial function in patients with AMI after thrombolytic therapy?
Population
37 patients with acute myocardial infarction who received thrombolytic therapy.
Design
Cohort
Follow-up
3-5 months
Authors
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May support viability assessment with rest SPECT post-thrombolysis; hypothesis-generating and requires prospective validation.
Observational (n=37)
Can rest 99mTc-sestamibi SPECT predict the recovery of myocardial function in patients with AMI after thrombolytic therapy?
p-value: p=<0.001
Resting 99mTc-sestamibi SPECT can be used to assess LV function status and predict the recovery of jeopardized myocardium after thrombolytic therapy in AMI patients.
Javadi et al. (2011) conducted an observational in ST elevation myocardial infarction (STEMI) (n=37). Rest 99mTc-sestamibi SPECT was evaluated on Recovery of myocardial function (change in wall motion scores) (p=<0.001). Resting 99mTc-sestamibi SPECT redistribution post-thrombolytic therapy predicted the recovery of segmental wall motion abnormality in patients with acute myocardial infarction (p<0.001).
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