Key result
Nonionic contrast media supplemented with electrolytes, such as iodixanol, reduce the risk of ventricular fibrillation compared to other agents when injected through a wedged catheter.
Why the study?
How do different types of contrast media affect cardiac electrophysiology and the risk of ventricular fibrillation during coronary injection?
Population
Experimental models and patients undergoing coronary angiography receiving contrast media
Comparison
Contrast media vs Different types of contrast media
Design
Review
Authors
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May favor electrolyte-supplemented nonionics like iodixanol in wedged injections; leaves open need for randomized confirmation.
How do different types of contrast media affect cardiac electrophysiology and the risk of ventricular fibrillation during coronary injection?
Nonionic contrast media supplemented with electrolytes, such as iodixanol, reduce the risk of ventricular fibrillation during coronary angiography, particularly when flow is restricted.
Jacobsen et al. (1995) conducted a review in Contrast media-induced electrophysiological effects. Contrast media vs. Different types of contrast media (high vs low osmolality, ionic vs nonionic) was evaluated on Electrophysiological effects and risk of ventricular fibrillation. Nonionic contrast media supplemented with electrolytes, such as iodixanol, reduce the risk of ventricular fibrillation compared to other agents when injected through a wedged catheter.
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