Key result
Surgical correction of grade III-V mitral valve insufficiency reduced left ventricular end-diastolic volume from 157 ml to 101 ml and normalized kinetic energy during the cardiac cycle.
Why the study?
Does surgical correction improve left ventricular function and intraventricular hemodynamics in patients with severe mitral valve insufficiency?
Cohort (n=144)
No
Does surgical correction improve left ventricular function and intraventricular hemodynamics in patients with severe mitral valve insufficiency?
Surgical correction of severe mitral insufficiency significantly reduces left ventricular volumes and normalizes kinetic energy and intraventricular blood flow patterns as assessed by vector analysis.
Surgical correction was associated with improved LV hemodynamics in severe mitral insufficiency; hypothesis-generating and requires randomized confirmation before practice change.
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Va et al. (2018) conducted a cohort in Mitral valve insufficiency (n=144). Surgical correction (mitral valve replacement and annuloplasty) vs. Pre-operative state and healthy controls was evaluated on Left ventricular end-diastolic volume (EDV). Surgical correction of grade III-V mitral valve insufficiency reduced left ventricular end-diastolic volume from 157 ml to 101 ml and normalized kinetic energy during the cardiac cycle.
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