Comparative antigenic analysis demonstrates strain- and clone-specific antigens in Trypanosoma cruzi, indicating that parasite strains consist of heterogeneous populations.
The antigenic constitution of two Trypanosoma cruzi strains and six cloned stocks was determined immunoelectrophoretically. Five to seven antigens common to all of the T. cruzi stocks were found. However, each stock also contained "strain-specific antigens," and five of the six cloned stocks presented "clone-specific antigens." These data demonstrate that a T. cruzi strain is composed of an antigenically heterogeneous population of organisms.
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Bongertz et al. (1983) studied this question.
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