Key result
Experimental infection of one partner with rhinovirus type 16 or 55 resulted in transmission rates of 41% and 33%, respectively, which depended on viral shedding and time spent together.
Why the study?
What are the rates and conditions of transmission of experimental rhinovirus colds between spouses?
Population
24 childless couples (n=48 individuals) where both partners initially lacked antibody to the challenge agent
Design
Other
Authors
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Spousal transmission depends on shedding and exposure duration; leaves open whether targeted interventions reduce household spread.
What are the rates and conditions of transmission of experimental rhinovirus colds between spouses?
Person-to-person transfer of rhinovirus depends heavily on time spent together and shedding of large amounts of virus by the donor, suggesting environmental manipulation could interrupt infection chains.
D'Alessio et al. (1976) studied Rhinovirus infection (n=48). Experimental infection with rhinovirus type 16 or type 55 was evaluated on Transmission between partners. Experimental infection of one partner with rhinovirus type 16 or 55 resulted in transmission rates of 41% and 33%, respectively, which depended on viral shedding and time spent together.
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