Key result
Elevated circulating catecholamines were found in about 50% of patients with labile hypertension and 30% with sustained hypertension, associated with higher heart rate and myocardial contractility.
Population
Patients with labile hypertension and patients with sustained essential hypertension
Design
Cross-sectional
Authors
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Suggests sympathetic hypertension subsets; hypothesis-generating and should not yet change practice.
Observational
Sub-groups of hypertensive patients exhibit increased sympathetic tone, characterized by elevated catecholamines, higher heart rate, increased contractility, and greater hypotensive response to beta-blockers.
Cousineau et al. (1978) conducted an observational in Labile and sustained essential hypertension. Elevated circulating catecholamines vs. Normal range catecholamines was evaluated on Proportion of patients with elevated circulating total catecholamine concentrations. Elevated circulating catecholamines were found in about 50% of patients with labile hypertension and 30% with sustained hypertension, associated with higher heart rate and myocardial contractility.
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