Key result
Carotid intima-media thickness measured by ultrasonography is a well-validated, independent predictor of future cardiovascular events and has utility as a screening tool for cardiovascular disease.
Carotid intima-media thickness measured by ultrasonography is a noninvasive, well-validated tool that serves as an independent predictor of future cardiovascular events.
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May refine cardiovascular risk stratification in select patients; leaves open routine screening utility pending prospective outcome trials.
Cardiovascular disease is the primary cause of death in most developed nations. Identifying an individual's cardiovascular risk remains a challenge. Traditional coronary-risk stratification is based on cardiovascular risk factors using risk score systems, which may not reliably identify atherosclerosis in asymptomatic individuals. Carotid intima-media thickness measured by ultrasonography is a noninvasive, well-validated tool that has been used as a surrogate for clinical coronary events. Carotid intima-media thickness has demonstrable utility as an independent predictor of future cardiovascular events. Recent data have improved our understanding of its applications as a screening tool for cardiovascular disease.
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Mookadam et al. (2011) conducted a review in Cardiovascular disease. Carotid intima-media thickness measurement was evaluated. Carotid intima-media thickness measured by ultrasonography is a well-validated, independent predictor of future cardiovascular events and has utility as a screening tool for cardiovascular disease.
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