Key result
Asphyxiated term neonates had significantly lower myocardial function assessed by peak systolic strain (-19.4% vs -21.7%; p<0.001) compared to healthy neonates.
Why the study?
Are longitudinal strain and strain rate by tissue Doppler more sensitive than fractional shortening for assessing reduced myocardial function in asphyxiated neonates?
Population
68 term neonates, comprising 20 asphyxiated neonates and 48 healthy controls.
Comparison
Tissue Doppler imaging to measure longitudinal… vs Fractional shortening assessment and healthy…
Design
Cohort
Follow-up
3 days (days 1, 2, and 3 of life)
Authors
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Strain may detect myocardial dysfunction missed by fractional shortening in asphyxiated neonates; hypothesis-generating and should not yet change practice.
Observational (n=68)
Are longitudinal strain and strain rate by tissue Doppler more sensitive than fractional shortening for assessing reduced myocardial function in asphyxiated neonates?
Absolute Event Rate: -19.4% vs -21.7%
p-value: p=< 0.001
Longitudinal strain and strain rate by tissue Doppler are more sensitive than fractional shortening for detecting reduced myocardial function in asphyxiated term neonates.
Nestaas et al. (2010) conducted an observational in Asphyxia (n=68). Asphyxia vs. Healthy term neonates was evaluated on Peak systolic strain (p=< 0.001). Asphyxiated term neonates had significantly lower myocardial function assessed by peak systolic strain (-19.4% vs -21.7%; p<0.001) compared to healthy neonates.
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