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Several 2‐aryl‐3,4‐dialkyltetrahydro‐1,3,4‐oxadiazines have been synthesized from 2‐(1,2‐dialkylhydrazino)ethanol (2) and aromatic aldehydes. Also, three 2‐aryl‐3,4‐dialkyltetrahydro‐1,3,4‐oxadiazin‐5‐ones were obtained from the reaction of 1,2‐dialkylglycolylhydrazine (5) and aromatic aldehydes. These compounds exhibited activity in the maximal electroshock seizure test.
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Milton J. Kornet (1996) studied this question.
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