Key result
After >1000 hours of sinus rhythm following Atrioverter implantation, atrial fibrillation remained inducible in 3 of 4 patients, demonstrating no return to normal atrial electrophysiology.
Why the study?
Does a long period of sinus rhythm reverse electrophysiological changes in patients with longer lasting recurrent AF?
Observational (n=4)
Does a long period of sinus rhythm reverse electrophysiological changes in patients with longer lasting recurrent AF?
Absolute Event Rate: 75% vs 75%
Long periods of sinus rhythm do not appear to reverse the atrial electrophysiological remodeling induced by long-standing recurrent atrial fibrillation.
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Prolonged sinus rhythm may not reverse atrial remodeling in recurrent AF; hypothesis-generating for larger studies on electrophysiological recovery.
Rodriguez et al. (1999) conducted an observational in Recurrent atrial fibrillation (n=4). Long period of sinus rhythm (>1000 hours) following Atrioverter implantation vs. Baseline (before implantation) was evaluated on Inducibility of atrial fibrillation by a single atrial premature beat. After >1000 hours of sinus rhythm following Atrioverter implantation, atrial fibrillation remained inducible in 3 of 4 patients, demonstrating no return to normal atrial electrophysiology.
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