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February 5, 2011Journal of Hypertension

New software analyses increase the reliability of measurements of retinal arterioles morphology by scanning laser Doppler flowmetry in humans

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Key result

The new software 'SLDF version 4.0' demonstrated high reliability for assessing retinal arteriolar structural parameters, with coefficients of variation significantly less than 10% for most measures.

Why the study?

Does the new software 'SLDF version 4.0' improve the reliability of measuring retinal arteriolar morphology compared to the old software in healthy persons and hypertensive patients?

Population

10 healthy persons and 18 patients with three types of arterial hypertension

Comparison

New software 'SLDF version 4.0' for scanning… vs Old software version

Design

Other

Follow-up

5 days (for test-retest study)

Authors

JHJoanna HaraźnyFriedrich-Alexander-Universität Erlangen-NürnbergURUlrike RaffApple (Israel)JWJürgen WelzenbachFriedrich-Alexander-Universität Erlangen-Nürnberg

Discussion

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Implication

Supports reliable retinal arteriolar assessment in hypertension research; leaves open clinical adoption pending prospective validation.

Study Design

Type

Observational (n=28)

Structured PICO

Does the new software 'SLDF version 4.0' improve the reliability of measuring retinal arteriolar morphology compared to the old software in healthy persons and hypertensive patients?

P
Population
10 healthy persons and 18 patients with arterial hypertension assessed for the reliability of retinal arteriolar morphology measurements.
E
Exposure
New software 'SLDF version 4.0' for scanning laser Doppler flowmetry
C
Comparator
Old software version
O
Outcome
Reliability (coefficients of variation) of structural parameters of retinal arterioles (vessel and lumen diameter, wall thickness, wall/lumen ratio, lumen/vessel diameter ratio, wall cross-sectional area)surrogate

The new SLDF version 4.0 software provides highly reliable in vivo measurements of retinal arteriolar structure, which is useful for assessing arteriolar remodeling in hypertension.

Cite This Study

Haraźny et al. (2011) conducted an observational in Arterial hypertension (n=28). New software 'SLDF version 4.0' for scanning laser Doppler flowmetry vs. Old software version was evaluated on Coefficients of variation of retinal arteriolar structural parameters. The new software 'SLDF version 4.0' demonstrated high reliability for assessing retinal arteriolar structural parameters, with coefficients of variation significantly less than 10% for most measures.

synapsesocial.com/papers/6a9e4a77beccc4fab9f58425https://doi.org/10.1097/hjh.0b013e328343c27a
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Also Consider

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