Key result
Presence of colon cancer is associated with changes in autonomic activity, namely parasympathetic-sympathetic imbalance in the form of sympathetic overdrive.
Observational
Colon cancer is associated with autonomic dysfunction characterized by sympathetic overdrive, which may contribute to impaired gastrointestinal motility.
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May support HRV/BPV as colon cancer biomarkers; hypothesis-generating and requires prospective validation before clinical use.
To the best of our knowledge, only two studies analyzed the relationship between HRV and carcinoembryonic antigen (CEA) in colon cancer patients. The aim of this study was to analyze changes in the autonomic activity of colon cancer patients using heart rate variability (HRV) and blood pressure variability (BPV) measures, and to verify if HRV and BPV parameters correlate with hemodynamic indices in this group and the plasma levels of CEA. Presence of colon cancer is associated with changes in autonomic activity, namely parasympathetic-sympathetic imbalance in form of sympathetic overdrive. Cancer-related autonomic dysfunction may contribute to impairment of gastrointestinal motility.
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Zygulska et al. (2018) conducted an observational in Colon cancer. Colon cancer was evaluated on Changes in autonomic activity (HRV and BPV) and correlation with hemodynamic indices and CEA. Presence of colon cancer is associated with changes in autonomic activity, namely parasympathetic-sympathetic imbalance in the form of sympathetic overdrive.
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