Key result
Obesity was not associated with an increased risk of 30-day mortality or postoperative complications after coronary artery bypass grafting compared to non-obese patients.
Why the study?
Does obesity affect early adverse events in patients undergoing isolated coronary artery bypass grafting?
Cohort (n=586)
No
Does obesity affect early adverse events in patients undergoing isolated coronary artery bypass grafting?
Obesity does not increase early adverse events after CABG and may be associated with lower rates of perioperative MI and need for hemodynamic support, supporting the obesity paradox.
Answers are grounded in this paper and cite their sources.
Obesity flags CABG patients with more comorbidities; leaves open whether BMI independently worsens early outcomes.
Background: The aim of this study was to quantify the effect of obesity on early results after coronary artery bypass grafting (CABG). Methods: A retrospective cohort study of patients underwent isolated CABG from January 2000 through December 2012 was conducted. 586 patients were classified into two groups: Obese (n = 100) BMI ≥ 30 kg/m2 and non-obese (n = 486) BMI ≤ 30kg/m2. Results: The obese patients included more women (p 0.01), hypertensives (p = 0.01) and dyslipidemics (p = 0001). The CPB, aortic champ times and number of bypass graft were similar between the groups (p = 0.35, p = 0.51 and p = 0.59 respectively). Also the composite of in-hospital mortality and postoperative complication didn’t differ between the groups. The incidence of perioperative myocardial infarction, and need for inotropic drugs or IABP were significantly less in obese patients (p = 0.028, p = 0.031 and p 0.01 respectively). Conclusions: The current study showed that obesity is not a risk factor of adverse events after CABG and continuous to give another aspect of the “obesity paradox”.
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Aithoussa et al. (2017) conducted a cohort in Coronary Artery Disease requiring CABG (n=586). Obesity (BMI ≥ 30 kg/m2) vs. Non-obese (BMI < 30 kg/m2) was evaluated on 30-day mortality (p=0.59). Obesity was not associated with an increased risk of 30-day mortality or postoperative complications after coronary artery bypass grafting compared to non-obese patients.
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