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January 1, 2017World Journal of Cardiovascular SurgeryOpen Access

Does Obesity Affect Early Results after Coronary Artery Bypass Grafting?

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Key result

Obesity was not associated with an increased risk of 30-day mortality (6% vs 4.7%, p=0.59) or postoperative complications after coronary artery bypass grafting compared to non-obese patients.

Why the study?

Does obesity affect early adverse events in patients undergoing isolated coronary artery bypass grafting?

Population

586 patients who underwent isolated coronary artery bypass grafting (CABG)

Comparison

Obesity (BMI ≥ 30 kg/m2) vs Non-obese (BMI ≤ 30 kg/m2)

Design

Cohort

Follow-up

in-hospital

Authors

MAMahdi AithoussaMohammed V UniversityNANoureddine AtmaniCadi Ayyad UniversityASAnis SeghrouchniMohammed V University

Discussion

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Member takes

Overview

Obesity flags CABG patients with more comorbidities; leaves open whether BMI independently worsens early outcomes.

Study Design

Type

Cohort (n=586)

Multicenter

No

Structured PICO

Does obesity affect early adverse events in patients undergoing isolated coronary artery bypass grafting?

P
Population
586 patients (mean age 58.6 years, 13.8% female) undergoing first isolated coronary artery bypass grafting, evaluated for in-hospital and 30-day postoperative outcomes.
E
Exposure
Obesity (BMI ≥ 30 kg/m2)
C
Comparator
Non-obese (BMI ≤ 30 kg/m2)
O
Outcome
Composite of in-hospital mortality and postoperative complicationcomposite

Main Result

Absolute Event Rate: 6% vs 4.7%

p-value: p=0.59

Obesity does not increase early adverse events after CABG and may be associated with lower rates of perioperative MI and need for hemodynamic support, supporting the obesity paradox.

Limitations

  • Retrospective design and conducted in a single center
  • BMI may not be the best tool to define obesity compared to waist circumference or waist-to-hip ratio
  • Heterogeneous clinical profile with unadjusted confounding factors like metabolic syndrome
  • Includes only in-hospital data and lacks mid-term and long-term follow-up

Cite This Study

Aithoussa et al. (2017) conducted a cohort in Coronary Artery Disease requiring CABG (n=586). Obesity (BMI ≥ 30 kg/m2) vs. Non-obese (BMI < 30 kg/m2) was evaluated on 30-day mortality (p=0.59). Obesity was not associated with an increased risk of 30-day mortality (6% vs 4.7%, p=0.59) or postoperative complications after coronary artery bypass grafting compared to non-obese patients.

synapsesocial.com/papers/6a9e57770bfbee156fd6f589https://doi.org/10.4236/wjcs.2017.710014
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Isolated Coronary Artery Bypass Grafting in Obese Individuals - A Propensity Matched Analysis of Outcomes -2011 · 41 citations
  2. 2The Influence of Body Mass Index on Outcomes in Patients Undergoing Cardiac Surgery: Does the Obesity Paradox Really Exist?2015 · 38 citations
  3. 3Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults1999 · 3,671 citations
  4. 4European system for cardiac operative risk evaluation (EuroSCORE)1999 · 3,398 citations