Key result
Continuing aspirin to within 7 days of CABG surgery was associated with significantly more drainage and blood product consumption in the first 12 postoperative hours compared to discontinuation.
Why the study?
Does continuing aspirin before CABG surgery increase bleeding complications in patients receiving antifibrinolytic agents?
Population
109 patients undergoing isolated, primary, on-pump coronary artery bypass grafting surgery performed by a…
Comparison
Aspirin 81 mg daily continued to within 7 days… vs Aspirin discontinued > 7 days before surgery…
Design
Cohort
Follow-up
Hospital stay
Authors
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May increase early bleeding after CABG; leaves open effects on overall outcomes in antifibrinolytic-treated patients.
Cohort (n=109)
No
Does continuing aspirin before CABG surgery increase bleeding complications in patients receiving antifibrinolytic agents?
Continuing low-dose aspirin before CABG increases early postoperative blood loss, but this does not adversely affect clinical outcomes or increase overall transfusion requirements.
Muthuswamy et al. (2013) conducted a cohort in Coronary artery bypass grafting (CABG) (n=109). Aspirin continuation to within 7 days of surgery vs. Aspirin discontinued > 7 days before surgery was evaluated on Drainage and blood product consumption during the first 12 postoperative hours. Continuing aspirin to within 7 days of CABG surgery was associated with significantly more drainage and blood product consumption in the first 12 postoperative hours compared to discontinuation.
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