Twice per week treatment versus five times per week. A radiotherapeutic clinical trial

In a clinical trial, tumour doses of 380 rads given twice weekly were compared with 200 rads given five times per week. The overall treatment time and other parameters of treatment remained the same and both regimes were tested on the same patient. The skin erythema was observed in six patients and tumour regression in five. Two hundred rads given five times per week appeared to be biologically more effective than 380 rads given twice weekly. A new trial is to be started raising the twice weekly dose to 400 rads.