Key result
The Fried frailty phenotype score was independently associated with long-term all-cause mortality in elderly survivors of acute coronary syndrome, with a hazard ratio of 1.35 per point increase.
Why the study?
The study was conducted to evaluate the 5 components of the Fried frailty phenotype for long-term outcomes in elderly survivors of acute coronary syndrome.
Does frailty assessment using the Fried phenotype predict long-term mortality in elderly survivors of acute coronary syndrome?
Population
342 consecutive elderly survivors of acute coronary syndrome
Comparison
Assessment of 5 Fried score components and albumin concentration before hospital discharge
Design
Cohort study
Follow-up
Median 8.7 years
Authors
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Fried frailty assessment stratifies long-term mortality risk in elderly ACS survivors; leaves open whether interventions targeting physical activity or gait speed improve outcomes.
Cohort (n=342)
No
Does frailty assessment using the Fried phenotype predict long-term mortality in elderly survivors of acute coronary syndrome?
Hazard Ratio: 1.35 (95% CI 1.17–1.57)
p-value: p=<.001
Frailty assessment using the Fried phenotype, particularly physical activity and gait speed, along with albumin levels, provides significant prognostic value for long-term mortality in elderly ACS survivors.
Sanchís et al. (2020) conducted a cohort in Acute coronary syndrome (n=342). Fried frailty phenotype score vs. Lower Fried score was evaluated on Postdischarge all-cause mortality (HR 1.35, 95% CI 1.17 to 1.57, p=<.001). The Fried frailty phenotype score was independently associated with long-term all-cause mortality in elderly survivors of acute coronary syndrome, with a hazard ratio of 1.35 per point increase.
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