Key result
Computed tomography angiography (CTA) measurements of the left atrial appendage ostium showed the strongest correlation (r=0.92) and narrowest limits of agreement with the actual Watchman device size compared to TEE and DSA.
Why the study?
To compare the results of CTA, TEE, and DSA measurements and analyze their accuracy, correlation, and consistency for Watchman left atrial appendage closure device sizing.
Does CTA provide more accurate and consistent measurements for Watchman device size selection compared to TEE and DSA in patients undergoing left atrial appendage closure?
Cohort (n=157)
No
Does CTA provide more accurate and consistent measurements for Watchman device size selection compared to TEE and DSA in patients undergoing left atrial appendage closure?
Effect estimate: r=0.92
p-value: p=<0.01
CTA provides the strongest relevance and concordance with actual Watchman device size for left atrial appendage closure compared to TEE and DSA, though it tends to measure larger ostium diameters.
CTA may aid Watchman sizing in LAAC; leaves open whether it improves outcomes versus TEE or DSA in prospective use.
PURPOSE: To compare the results of computed tomography angiography (CTA), transesophageal echocardiography (TEE), and digital subtraction angiography (DSA) measurements and analyze their accuracy, correlation, and consistency in patients who have successfully undergone left atrial appendage closure (LAAC). MATERIALS AND METHODS: A total of 157 non-valvular atrial fibrillation (AF) patients who underwent LAAC with Watchman devices were included in the study. The maximum diameter and depth of LAA were recorded using CTA, TEE, and DSA. Correlations and agreements were compared. RESULTS: The LAAC procedure was performed successfully in all patients using the Watchman device. There was no significant difference between DSA and TEE measurements of the diameter of the LAA ostium. LAA ostium diameter obtained by CTA, however, was greater than that from DSA and TEE. Correlations were good between LAA ostium diameter measured by TEE, CTA, and DSA and Watchman device size. DSA measurements and actual device size showed the widest limits of agreement, followed by TEE; CTA measurements showed the narrowest limits of agreement. For LAA depth measurements, mean CTA measurements were higher than those of TEE and DSA. There was no significant difference in depth measurements among the three imaging modalities. CONCLUSION: CTA, TEE, and DSA measurements exhibited good correlations with Watchman device size. The ostium diameter and depth of the LAA measured by CTA were greater than those measured by TEE and DSA. The relevance and concordance of CTA measurements were the strongest.
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Ruan et al. (2022) conducted a cohort in Non-valvular atrial fibrillation (n=157). Computed tomography angiography (CTA) vs. Transesophageal echocardiography (TEE) and digital subtraction angiography (DSA) was evaluated on Correlation of LAA ostium diameter with Watchman device size (r=0.92, p=<0.01). Computed tomography angiography (CTA) measurements of the left atrial appendage ostium showed the strongest correlation (r=0.92) and narrowest limits of agreement with the actual Watchman device size compared to TEE and DSA.
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