Key result
Current data from nonrandomized cohort studies suggest that postcardiac arrest patients without ST-segment elevation may benefit from an aggressive approach to postresuscitation care.
Why the study?
Does an aggressive approach to postresuscitation care (targeted temperature management and early coronary angiography) improve outcomes in comatose post-cardiac arrest patients without ST-segment elevation?
Does an aggressive approach to postresuscitation care (targeted temperature management and early coronary angiography) improve outcomes in comatose post-cardiac arrest patients without ST-segment elevation?
Aggressive postresuscitation care, including targeted temperature management and early coronary angiography, may benefit comatose post-cardiac arrest patients even without ST-segment elevation, though increased stent thrombosis risk requires further study.
Should not yet change postarrest care without ST elevation; leaves open benefit of aggressive strategies pending randomized trials.
Targeted temperature management and early coronary angiography have become the standard of care for postcardiac arrest patients remaining comatose and with ST-segment elevation on the ECG. Less clear is the optimal approach for similar patients without ST-segment elevation on the postresuscitation ECG. However, current data from nonrandomized cohort studies suggest that many of these patients also benefit from an aggressive approach to postresuscitation care. Recent reports of increased stent thrombosis in the postarrest population need further exploration.
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Kanakadandi et al. (2015) conducted a review in Out-of-hospital cardiac arrest. Targeted temperature management and early coronary angiography was evaluated. Current data from nonrandomized cohort studies suggest that postcardiac arrest patients without ST-segment elevation may benefit from an aggressive approach to postresuscitation care.
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