Key result
Pulsed Wave Tissue Doppler Imaging successfully distinguished pathological from physiological left ventricular hypertrophy, revealing significantly lower E' velocities (7.2 vs 9.4 cm/sec) and higher E/E' ratios (10.6 vs 7.8) in hypertensive subjects compared to master athletes (p<0.001).
Why the study?
Does Pulsed Wave Tissue Doppler Imaging distinguish pathological from physiological left ventricular hypertrophy in middle-aged subjects with mild-moderate LVM increase?
Population
160 middle-aged subjects matched for age, sex, and body mass index. Key inclusion: mild-moderate left…
Comparison
Pulsed Wave Tissue Doppler Imaging to assess… vs Conventional Pulsed Wave (PW) Doppler analysis
Design
Cross-sectional
Authors
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TDI may differentiate LVH types in middle-aged adults; leaves open its impact on management or outcomes pending prospective validation.
Cross-Sectional (n=160)
No
Does Pulsed Wave Tissue Doppler Imaging distinguish pathological from physiological left ventricular hypertrophy in middle-aged subjects with mild-moderate LVM increase?
Absolute Event Rate: 7.2% vs 9.4%
p-value: p=<0.001
Pulsed Wave Tissue Doppler Imaging can effectively distinguish physiological left ventricular hypertrophy in athletes from pathological hypertrophy in hypertensive patients by unmasking pseudonormal diastolic patterns.
Galanti et al. (2009) conducted a cross-sectional in Left ventricular hypertrophy (n=160). Essential hypertension (pathological LVH) vs. Master athletes (physiological LVH) was evaluated on Diastolic function assessed by PW-TDI (E' velocity) (p=<0.001). Pulsed Wave Tissue Doppler Imaging successfully distinguished pathological from physiological left ventricular hypertrophy, revealing significantly lower E' velocities (7.2 vs 9.4 cm/sec) and higher E/E' ratios (10.6 vs 7.8) in hypertensive subjects compared to master athletes (p<0.001).
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