Key result
Delaying permanent pacemaker implantation to three weeks or more after cardiac transplantation significantly increased evidence of pacing at three months (78.6% vs 37.5%, P=0.03).
Why the study?
Does delaying permanent pacemaker implantation to three weeks or more post transplantation improve appropriate pacemaker utilization in cardiac transplant recipients?
Observational (n=332)
No
Does delaying permanent pacemaker implantation to three weeks or more post transplantation improve appropriate pacemaker utilization in cardiac transplant recipients?
Absolute Event Rate: 78.6% vs 37.5%
p-value: p=0.03
Delaying permanent pacemaker implantation until at least three weeks after cardiac transplantation may improve the appropriate selection of patients who will remain pacemaker-dependent.
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May support delaying PPM implantation post-transplant to optimize dependency assessment; hypothesis-generating and requires prospective trials before practice change.
Holt et al. (1996) conducted an observational in Cardiac transplantation (n=332). Delaying permanent pacemaker implantation to ≥3 weeks vs. Implantation at <3 weeks was evaluated on Evidence of pacing on 12 lead electrocardiogram at three months (p=0.03). Delaying permanent pacemaker implantation to three weeks or more after cardiac transplantation significantly increased evidence of pacing at three months (78.6% vs 37.5%, P=0.03).
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