Why the study?
Does replacement of heart valves with autologous fascia lata grafts provide good clinical and haemodynamic results in patients requiring valve replacement?
Observational (n=70)
Yes
Does replacement of heart valves with autologous fascia lata grafts provide good clinical and haemodynamic results in patients requiring valve replacement?
Answers are grounded in this paper and cite their sources.
Autologous fascia lata grafts for heart valve replacement showed promising early clinical and hemodynamic results without the need for anticoagulation.
Autologous fascia lata graft valves attached on to a Dacron-covered titanium frame have been used since April, 1969, at the General Infirmary at Leeds and the National Heart Hospital and Guy's Hospital, London. Seventy-seven such grafts have been inserted into 70 patients with very good immediate and short-term clinical and haemodynamic results. No systemic emboli have occurred although anticoagulants have not been used. The technique of preparing supported autologous fascia lata grafts for clinical use is outlined in detail and the surgical implantation of these grafts into the mitral, aortic, and tricuspid areas is described.
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Ionescu et al. (1970) conducted an observational in Valvular heart disease requiring replacement (n=70). Autologous fascia lata graft valves attached to a Dacron-covered titanium frame was evaluated on Systemic emboli.
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