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September 1, 2013Open Access

In medically treated acute type B aortic dissection, having a single entry tear was associated with a significantly higher median aortic growth rate (5.8 mm/year) compared to having two entry tears (0.98 mm/year, P=0.01).

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Why the study?

Is the number of identifiable entry tears associated with aortic growth in long-term acute type B aortic dissection?

Population

Patients with long-term acute type B aortic dissection (ABAD)

Design

Cohort

Key result

In medically treated acute type B aortic dissection, having a single entry tear was associated with a significantly higher median aortic growth rate (5.8 mm/year) compared to having two entry tears (0.98 mm/year, P=0.01).

Authors

JTJip L. TolenaarJHJoost A. van HerwaardenHVHence J.M. Verhagen

Discussion

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Member takes

Overview

May warrant intensified surveillance for single-entry-tear patients; hypothesis-generating for tear-number-based risk models in type B dissection.

Study Design

Type

Cohort (n=60)

Multicenter

Yes

Structured PICO

Is the number of identifiable entry tears associated with aortic growth in long-term acute type B aortic dissection?

P
Population
60 medically treated patients with acute type B aortic dissection, median age 59.7 years, followed for a median of 22 months to assess aortic growth.
E
Exposure
Number of identifiable entry tears detected between the true and false lumens
O
Outcome
Aortic growth (degree of aortic dilatation in the long term)surrogate

Main Result

Absolute Event Rate: 5.8% vs 0.98%

p-value: p=0.01

This study aims to determine if the number of entry tears can predict long-term aortic growth in patients with type B aortic dissection.

Limitations

  • Clinical information of the study population was unavailable
  • Entry tears may possibly have been missed on the baseline CTAs
  • Entry tears can be smaller than the slice thickness of CTA scans
  • Other imaging predictors such as the size of the entry tears may influence aortic growth

Cite This Study

Tolenaar et al. (2013) conducted a cohort in Acute type B aortic dissection (n=60). One entry tear vs. Two entry tears was evaluated on Aortic growth rate (mm/year) (p=0.01). In medically treated acute type B aortic dissection, having a single entry tear was associated with a significantly higher median aortic growth rate (5.8 mm/year) compared to having two entry tears (0.98 mm/year, P=0.01).

synapsesocial.com/papers/6a9e8755f835b2283e3800a8https://doi.org/10.3978/j.issn.2225-319x.2013.09.05
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Role of entry tear size in type B aortic dissection.2014 · 19 citations
  2. 2Partial thrombosis of the false lumen influences aortic growth in type B dissection.2014 · 9 citations
  3. 3Predicting Aneurysmal Degeneration in Uncomplicated Residual Type B Aortic Dissection2024 · 2 citations
  4. 4Predicting aortic enlargement in type B aortic dissection.2014 · 34 citations
  5. 5Differences in the Area of Proximal and Distal Entry Tears at CT Angiography Predict Long-term Clinical Outcomes in Aortic Dissection2021 · 20 citations