Key result
A sensorless estimation method successfully estimated pressure head by compensating for viscosity changes in an adult goat, though in vivo accuracy was lower than in vitro tests.
Population
Adult goat (n=1) implanted with two centrifugal blood pumps as a total artificial heart
Comparison
Estimation method for instantaneous flow rate… vs True values of pressure head and flow rate
Design
Preclinical
Authors
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Sensorless methods remain preclinical with reduced in vivo accuracy; leaves open refinements needed before human translation.
A sensorless estimation method for flow rate and pressure head in continuous-flow artificial hearts demonstrated feasibility in an acute animal model, though with lower accuracy than in vitro.
Tanaka et al. (2003) studied Total artificial heart evaluation (n=1). Sensorless estimation method for flow rate and pressure head vs. True values measured by sensors was evaluated on Estimation accuracy of pressure head and flow rate during blood viscosity changes. A sensorless estimation method successfully estimated pressure head by compensating for viscosity changes in an adult goat, though in vivo accuracy was lower than in vitro tests.
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