Key result
Dynamic cardiomyoplasty pacing at 100 contractions per minute maintained latissimus dorsi muscle force but severely hampered relaxation, potentially diminishing support for the failing heart.
Why the study?
Does a pacing protocol of 100 contractions per minute affect latissimus dorsi muscle relaxation in dynamic cardiomyoplasty?
Does a pacing protocol of 100 contractions per minute affect latissimus dorsi muscle relaxation in dynamic cardiomyoplasty?
The standard pacing protocol of 100 contractions per minute in dynamic cardiomyoplasty severely impairs muscle relaxation, suggesting a lower maximal stimulation rate is necessary to prevent muscle damage.
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Pacing at 100 contractions per minute may compromise dynamic cardiomyoplasty support; leaves open optimal rates for muscle preservation in translational research.
Lucas et al. (1992) studied severe heart failure (n=8). Dynamic cardiomyoplasty pacing protocol was evaluated on Latissimus dorsi muscle contraction characteristics (force and relaxation). Dynamic cardiomyoplasty pacing at 100 contractions per minute maintained latissimus dorsi muscle force but severely hampered relaxation, potentially diminishing support for the failing heart.