Key result
The anatomy of deep vein thrombosis in women using low-estrogen oral contraceptives was identical to that in women using high-estrogen pills and similar to DVT in pregnant women.
Why the study?
Does the estrogen dose in oral contraceptives affect the anatomical site and side of deep vein thrombosis in women?
Observational (n=277)
Does the estrogen dose in oral contraceptives affect the anatomical site and side of deep vein thrombosis in women?
The anatomical distribution of deep vein thrombosis in women using oral contraceptives resembles that of pregnancy-associated DVT and is not influenced by the estrogen dose of the pill.
Answers are grounded in this paper and cite their sources.
Supports uniform DVT anatomy across OC estrogen doses; hypothesis-generating for shared mechanisms with pregnancy-related thrombosis.
The anatomy of the thrombus in acute deep vein thrombosis (DVT) in women using oral contraceptives was studied in 277 reports on DVT received by the Swedish Adverse Drug Reaction Advisory Committee (SADRAC). The study revealed a similarity between the anatomy of DVT in women on oral contraceptives and that of DVT in pregnant women, suggesting a pharmacologic influence of the hormones in the pill on the pathogenesis of DVT in women on oral contraceptives. The anatomy of DVT in women on low-estrogen pills was identical with that of DVT in women on high-estrogen pills, suggesting an identical pharmacologic influence of the two types of pill on the pathogenesis of DVT in women on oral contraceptives.
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A Kierkegaard (1985) conducted an observational in Acute deep vein thrombosis (n=277). Oral contraceptives vs. Pregnant women / High-estrogen pills was evaluated on Anatomy of the thrombus. The anatomy of deep vein thrombosis in women using low-estrogen oral contraceptives was identical to that in women using high-estrogen pills and similar to DVT in pregnant women.
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