Key result
Treatment of severe complicated hypertension resulted in an overall survival of 60% at 5 years, 43% at 10 years, and 21% at 15 years.
Why the study?
Does antihypertensive treatment improve long-term survival in patients with severe complicated hypertension?
Population
191 patients with severe complicated hypertension admitted to a clinic between 1951 and 1969
Comparison
Antihypertensive treatment vs General population (for survival curve comparison)
Design
Cohort
Follow-up
up to 18 years (1951 to December 1969)
Authors
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Poor long-term survival persists after treatment of severe complicated hypertension; leaves open whether earlier intervention improves outcomes.
Cohort (n=191)
Does antihypertensive treatment improve long-term survival in patients with severe complicated hypertension?
Long-term follow-up of treated severe hypertension shows significant early mortality from renal and cerebral causes, and later mortality from myocardial infarction, highlighting the need for early treatment.
Barnett et al. (1973) conducted a cohort in Severe complicated hypertension (n=191). Treatment of severe hypertension vs. General population was evaluated on Overall survival. Treatment of severe complicated hypertension resulted in an overall survival of 60% at 5 years, 43% at 10 years, and 21% at 15 years.
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