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August 9, 2011Interactive Cardiovascular and Thoracic SurgeryOpen Access

Learning what works in surgical cryoablation of atrial fibrillation: results of different application techniques and benefits of prospective follow-up

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Key result

Biatrial cryo-maze yielded a higher rate of freedom from AF without antiarrhythmic drugs at 12 months (82%) compared to epicardial (69%) and endocardial (74%) left atrial procedures.

Why the study?

Does the application technique of concomitant surgical cryoablation affect rhythm outcomes in cardiac surgical patients with atrial fibrillation?

Population

115 cardiac surgical patients with atrial fibrillation undergoing concomitant surgical ablation

Comparison

Concomitant surgical argon-based cryoablation… vs Comparison among three application techniques…

Design

Cohort

Follow-up

12 months

Authors

AAAnders AlbågeUppsala University HospitalMPMikael PéterffyKarolinska University HospitalGKGöran KällnerInterventional / Structural Cardiology

Discussion

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Implication

May favor biatrial cryo-maze for sinus rhythm in surgical AF; extends observational data but leaves open randomized confirmation.

Study Design

Type

Cohort (n=115)

Multicenter

No

Structured PICO

Does the application technique of concomitant surgical cryoablation affect rhythm outcomes in cardiac surgical patients with atrial fibrillation?

P
Population
115 cardiac surgical patients with atrial fibrillation undergoing concomitant surgical argon-based cryoablation, followed for 12 months.
E
Exposure
Concomitant surgical argon-based cryoablation using three different application techniques (epicardial left atrium, endocardial left atrium, biatrial cryo-maze)
C
Comparator
Comparison among three application techniques: epicardial left atrium (EpiLA), endocardial left atrium (EndoLA), and biatrial cryo-maze
O
Outcome
Sinus or pacing rhythm, free of AF without antiarrhythmic drugs at 12 months

Main Result

Absolute Event Rate: 82% vs 69%

A complete biatrial lesion set (cryo-maze) yields a higher success rate for maintaining sinus rhythm without antiarrhythmic drugs at 12 months compared to left atrial procedures alone during concomitant cardiac surgery.

Cite This Study

Albåge et al. (2011) conducted a cohort in Atrial fibrillation in cardiac surgical patients (n=115). Biatrial cryo-maze vs. Epicardial or endocardial left atrial cryoablation was evaluated on Sinus or pacing rhythm, free of AF without antiarrhythmic drugs at 12 months. Biatrial cryo-maze yielded a higher rate of freedom from AF without antiarrhythmic drugs at 12 months (82%) compared to epicardial (69%) and endocardial (74%) left atrial procedures.

synapsesocial.com/papers/6a9e979037bba822732cbbcchttps://doi.org/10.1510/icvts.2011.280735

Topics

Atrial fibrillationPersistent AF managementAnticoagulation in AFAF ablation outcomes
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Medium-term outcome of different surgical methods to cure atrial fibrillation: is less worse?2007 · 16 citations
  2. 2Impact of the maze procedure on the stroke rate in patients with atrial fibrillation1999 · 365 citations
  3. 3The biatrial cryo-maze procedure for treatment of atrial fibrillation: A single-center experience2011 · 8 citations
  4. 4Surgical Treatment of Atrial Fibrillation Using Argon-Based Cryoablation During Concomitant Cardiac Procedures2005 · 59 citations
  5. 5A randomized double-blind study of epicardial left atrial cryoablation for permanent atrial fibrillation in patients undergoing mitral valve surgery: the SWEDish Multicentre Atrial Fibrillation study (SWEDMAF)2007 · 156 citations