Key result
Verapamil prolongs atrioventricular conduction proximal to the bundle of His, likely due to an intrinsic action.
Why the study?
Does verapamil affect sinus node, atrioventricular, and intraventricular conduction?
Population
Subjects undergoing electrocardiograms and His bundle electrograms
Design
Other
Authors
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May inform verapamil use in supraventricular arrhythmias; hypothesis-generating for conduction effects.
Observational
Does verapamil affect sinus node, atrioventricular, and intraventricular conduction?
Verapamil prolongs AV conduction proximal to the bundle of His, providing a mechanistic explanation for its efficacy in treating paroxysmal supraventricular arrhythmias.
Husaini et al. (1973) conducted an observational in supraventricular tachyarrhythmias. Verapamil was evaluated on Atrioventricular (AV) conduction time. Verapamil prolongs atrioventricular conduction proximal to the bundle of His, likely due to an intrinsic action.
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