Key result
Ischaemia induced by dobutamine stress testing in patients with acute myocardial infarction leads to a significant decrease in stroke volume with no change in pulmonary artery wedge pressure (P<0.05).
Why the study?
Does dobutamine-induced ischaemia alter haemodynamic variables in patients with a first acute myocardial infarction?
Population
15 patients with a first acute myocardial infarction
Comparison
Dobutamine infusion at doses from 5 to a maximum… vs Patients without dobutamine-induced ischaemia…
Design
Cross-sectional
Authors
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May reduce stroke volume during dobutamine stress in acute MI without raising wedge pressure; hypothesis-generating and requires prospective confirmation.
Observational (n=15)
Does dobutamine-induced ischaemia alter haemodynamic variables in patients with a first acute myocardial infarction?
p-value: p=<0.05
Dobutamine-induced ischaemia in patients with a recent myocardial infarction leads to a decrease in stroke volume without changing pulmonary artery wedge pressure.
Piérard et al. (1989) conducted an observational in first acute myocardial infarction (n=15). Ischaemia induced by dobutamine stress testing vs. Absence of ischaemia was evaluated on Haemodynamic response curves (thermodilution cardiac output, stroke volume and systemic vascular resistance) (p=<0.05). Ischaemia induced by dobutamine stress testing in patients with acute myocardial infarction leads to a significant decrease in stroke volume with no change in pulmonary artery wedge pressure (P<0.05).
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