Why the study?
Does dobutamine infusion during echocardiography stress testing elicit different systemic cardiovascular responses in patients with versus without myocardial ischaemia?
Population
18 patients undergoing dobutamine echocardiography stress test for coronary artery disease, including 9…
Comparison
Dobutamine infusion up to 40 micrograms kg-1… vs Patients without myocardial ischaemia versus…
Design
Cross-sectional
Follow-up
During stress test
Authors
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Ischaemia may blunt dobutamine-induced chronotropic and output responses during stress echocardiography; hypothesis-generating for compensatory hemodynamics and needs prospective validation.
Does dobutamine infusion during echocardiography stress testing elicit different systemic cardiovascular responses in patients with versus without myocardial ischaemia?
The inotropic, chronotropic, and vasodilatory effects of dobutamine balance the ischaemic impairment of left ventricular function during stress testing, maintaining systemic hemodynamics.
Aakhus et al. (1995) studied this question.
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