Key result
Placement of the pulmonary artery wedge catheter above the left atrium with 5 cm H2O of PEEP caused a 5 mm Hg gradient between PAWP and LAP in normovolemic dogs.
Population
19 anesthetized dogs
Design
Preclinical
Authors
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May mislead LAP estimation via PAWP during PEEP; leaves open human applicability.
Accurate estimation of left atrial pressure using pulmonary artery wedge pressure requires fluid continuity, which can be disrupted by catheter placement above the left atrium, increased PEEP, or hypovolemia.
Kane et al. (1978) studied this question. Placement of pulmonary artery wedge catheter above the left atrium with PEEP was evaluated on Gradient between pulmonary artery wedge pressure (PAWP) and left atrial pressure (LAP). Placement of the pulmonary artery wedge catheter above the left atrium with 5 cm H2O of PEEP caused a 5 mm Hg gradient between PAWP and LAP in normovolemic dogs.
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