Key result
General anesthesia for emergency cesarean section in severe preeclampsia was associated with significantly higher maternal mortality compared to spinal anesthesia (25.9% vs 1.4%; P<0.001).
Why the study?
Does general anesthesia compared to spinal anesthesia affect fetomaternal outcomes in severe preeclamptic women undergoing emergency cesarean section?
Population
173 severe preeclamptic women undergoing emergency cesarean section, mostly primigravid and nulliparous
Comparison
General anesthesia vs Spinal anesthesia
Design
Cohort
Authors
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Supports spinal preference in severe preeclampsia cesareans when feasible; leaves open need for randomized confirmation of causality.
Observational (n=173)
Does general anesthesia compared to spinal anesthesia affect fetomaternal outcomes in severe preeclamptic women undergoing emergency cesarean section?
Absolute Event Rate: 25.9% vs 1.4%
p-value: p=< 0.001
In severe preeclamptic women undergoing emergency cesarean section, general anesthesia is associated with significantly higher maternal and neonatal mortality and critical care requirements compared to spinal anesthesia.
Chattopadhyay et al. (2014) conducted an observational in Severe preeclampsia (n=173). General anesthesia vs. Spinal anesthesia was evaluated on Maternal mortality (p=< 0.001). General anesthesia for emergency cesarean section in severe preeclampsia was associated with significantly higher maternal mortality compared to spinal anesthesia (25.9% vs 1.4%; P<0.001).
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