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August 27, 2004Critical Care Medicine

Amplitude spectrum area: Measuring the probability of successful defibrillation as applied to human data

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Why the study?

Does the amplitude spectral area (AMSA) algorithm predict successful defibrillation in victims of out-of-hospital cardiac arrest?

Population

46 victims of out-of-hospital cardiac arrest due to ventricular fibrillation (108 defibrillation attempts)

Design

Cohort

Authors

CYClayton YoungJBJoe BiseraUniversity of Southern CaliforniaSGStacy GehmanPhilips (United States)

Discussion

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Overview

AMSA >13.0 mV-Hz may aid defibrillation timing in OHCA; hypothesis-generating and requires prospective validation before practice change.

Structured PICO

Does the amplitude spectral area (AMSA) algorithm predict successful defibrillation in victims of out-of-hospital cardiac arrest?

P
Population
46 victims of out-of-hospital cardiac arrest due to ventricular fibrillation (108 defibrillation attempts)
I
Intervention
Amplitude spectral area (AMSA) algorithm analysis of 3 seconds of ventricular fibrillation preceding shock delivery
O
Outcome
Successful conversion to an organized viable rhythm, including the return of spontaneous circulationsurrogate

The amplitude spectral area (AMSA) algorithm can predict the success of electrical defibrillation with high sensitivity and specificity, potentially minimizing interruptions in chest compressions and myocardial injury from ineffective shocks.

Cite This Study

Young et al. (2004) studied this question.

synapsesocial.com/papers/6a9ee9b2e2d0fc9581be7b50https://doi.org/10.1097/01.ccm.0000134353.55378.88
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1High-Energy Defibrillation Increases the Severity of Postresuscitation Myocardial Dysfunction1997 · 285 citations
  2. 2Amplitude of Ventricular Fibrillation Waveform and Outcome After Cardiac Arrest1985 · 245 citations
  3. 3Optimizing timing of ventricular defibrillation2001 · 140 citations
  4. 4Scaling Exponent Predicts Defibrillation Success for Out-of-Hospital Ventricular Fibrillation Cardiac Arrest2001 · 110 citations
  5. 5Ventricular Fibrillation Scaling Exponent Can Guide Timing of Defibrillation and Other Therapies2004 · 88 citations