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May 1, 2002Biorheology

Breaking symmetry in non‐planar bifurcations: Distribution of flow and wall shear stress

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Population

Hypothetical non-planar bifurcation model for computational fluid dynamics (CFD) simulation

Design

Preclinical

Authors

YLYiling LuUniversity of DerbyXLXi‐Yun LuUniversity of Science and Technology of ChinaLZLixian ZhuangUniversity of Science and Technology of China

Discussion

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Overview

May alter local hemodynamics; leaves open its role in human vascular disease.

Structured PICO

P
Population
Hypothetical non-planar bifurcation model for computational fluid dynamics (CFD) simulation
I
Intervention
Non-planarity in one of the two daughter vessels
O
Outcome
Distribution of fluid flows and wall shear stressessurrogate

Computational modeling demonstrates that non-planarity in blood vessels significantly alters flow distribution and wall shear stress, highlighting its potential role in vascular pathophysiology.

Cite This Study

Lu et al. (2002) studied this question.

synapsesocial.com/papers/6a9ef893a926c8a8b007b19ahttps://doi.org/10.1177/0006355x2002039003004021
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  5. 5Atheroma and arterial wall shear - Observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis1971 · 1,359 citations